CSC Plasticity and Tumor Progression

Cancer stem cells (CSCs) exhibit remarkable plasticity, allowing them to switch between stem-like and differentiated states in response to microenvironmental cues. This track explores the mechanisms underlying CSC plasticity and how it contributes to tumor progression, metastasis, and therapeutic resistance. Researchers study the factors that regulate transitions between CSC and non-CSC states, including epigenetic changes and signaling pathways. Targeting CSC plasticity could prevent tumors from adapting to therapies and evolving into more aggressive forms. By understanding how plasticity drives tumor heterogeneity and survival, researchers aim to develop therapies that eliminate CSCs and block tumor progression, reducing the chances of relapse.

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