Inflammation and CSC Activation

Chronic inflammation plays a significant role in cancer initiation and progression, often leading to the activation of cancer stem cells (CSCs). This track investigates the links between inflammatory signaling pathways—such as NF-κB, IL-6, and TNF-α—and the activation of CSCs. Researchers explore how inflammation within the tumor microenvironment promotes CSC self-renewal, survival, and metastasis. Targeting the inflammatory signals that support CSCs could lead to novel therapeutic strategies that disrupt this relationship, limiting tumor growth and progression. This research highlights the importance of anti-inflammatory agents in cancer treatment, offering new opportunities to inhibit CSC-driven malignancies by reducing inflammation.

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