14^thInternational Conference on Cancer Stem Cell & Oncology Research March 21-22, 2022 Amsterdam, Netherlands

Neuro-oncology is the study of cancers within the brain and medulla spinalis Cancers within the nervous system are usually serious and critical. In some cases, survival is extended using chemotherapy and radiation therapy.

Precision medicine, also called personalized medicine, is an approach to treating cancer that is customized to each individual patient. A major factor in precision medicine is an individual’s DNA molecules, gene sequences and unique genetic history. Cancer is the result of a genetic malfunction that causes cells to develop out of control, creating tumors. Understanding a person’s complete set of DNA, also called the genome, is the first step in using precision medicine to guide treatment. The more researchers know about genetic sequencing and DNA analysis of cancer tumors, the more specialized treatment options may be available, especially if a person’s cancer stops responding to standard treatment.

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  Genetic makeup


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  Environmental factors


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  Lifestyle choices

Cancer stem cells are the small number of cells within a tumor that drive the tumor's growth. These cells generally make up just 1% to 3% of all cells in a tumor. Cancer research focuses on stem cells present in malignant tumors. Researchers believe current cancer treatments sometimes fail because they do not destroy the cancer stem cells. Consider cancer as a weed: the stem cells are the foundation while the remaining majority of the cells are a part of the weed above ground. If you remove only the leaves but not the basis, the weed will grow back. The identical is true for cancer: if you are doing not kill the cancer stem cells, the cancer is probably going to return.

Cancer stem cell evidence declares the presence of the a little population of disease cells with characteristic functions taking into account protection from radio-chemotherapy organized and expanded metastatic ability.  

A growing body of evidence indicates that the tumor microenvironment contributes to tumor growth and viability, while significant advances are being made within the understanding of cancer stem cells and tumor initiating cells. The session will discuss on breaking developments on novel tumor-killing strategies and preclinical and clinical projects which are exploiting cancer stem cells, the inflammatory component of tumors, and therefore the tumor microenvironment for therapeutic intervention.

Pancreatic cancer stem cells have some similarities to cancer stem cells found in other kinds of cancer; however, there also appear to be some significant differences. This is often why it's important to review the function of those cells within the specific cancer during which these cells arise to best understand their function. No matter the organ within which they're found, cancer stem cells appear to be answerable for the propagation of cancer and for its spread to other organs within the body. But they will do that in several ways.

Breast cancer stem cells - the primary to be identified in an exceedingly solid tumour - were discovered in 2003 by scientists at the U-M Comprehensive Cancer Centre. U-M scientists found that just some cancer stem cells are chargeable for the expansion and spread of carcinoma. Unless the cancer stem cells are destroyed, the tumour is probably going to come back and spread malignant cells to other parts of the body, a process called metastasis.

Prostate cancer is now a standard disease in men over 50 years old. Medical therapies for glandular carcinoma are supported discoveries from the mid-twentieth century, and within the future are rarely curative. Most treatments are directed towards an androgen receptor-expressing, highly proliferative target cell, which does indeed form the overwhelming majority of cells during a prostate tumour. However, by invoking the existence of a cancer vegetative cell which, like normal epithelial stem cells within the prostate, doesn't express androgen receptor and is comparatively quiescent, the observed resistance to most medical therapies are often explained. The phenotype of the glandular cancer stem cells is that of a basal cell and cultures derived from cancers, but not benign tissues, express a spread of prostate cancer-associated RNAs.

Gastric cancer could be a significant global ill health. It's the fifth most typical cancer and third leading reason for cancer-related death worldwide. Despite advances in treatment, overall prognosis remains poor, because of tumour relapse and metastasis. There's an urgent need for novel therapeutic approaches to boost clinical outcomes in gastric cancer. The cancer somatic cell (CSC) model has been proposed to elucidate the high rate of relapse and subsequent resistance of cancer to current systemic treatments. CSCs are identified in many solid malignancies, including gastric cancer, and have significant clinical implications, as targeting the CSC population could also be essential in preventing the recurrence and spread of a tumour.

Lung cancer remains a significant explanation for cancer-related lethality due to high incidence and recurrence in spite of great advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic characteristics including high proliferative capacity, multipotent differentiation, drug resistance and long lifespan relative to other cells. Stem cell signalling and differentiation pathways are maintained within distinct cancer types, and destabilization of this machinery may participate in maintenance of cancer stem cells. Characterization of carcinoma stem cells is a section of active research and is critical for developing novel therapies. This review summarizes the present knowledge on Stem cell signalling pathways and cell markers wont to identify the carcinoma stem cel

The cancer Stem cell (CSC) model proposes that tumor development and progression are fuelled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor-initiating capacity. Ovarian carcinoma, supported its biological features and clinical evolution, appears as a prototypical example of CSC-driven disease. Indeed, ovarian cancer stem cells (OCSC) would account not just for the first tumor growth, the peritoneal spread and also the relapse, but also for the event of chemo resistance, thus having profound implication for the treatment of this deadly disease.

Acquired immune deficiency syndrome (AIDS) is a disease of the immune system caused by human immunodeficiency virus (HIV).  HIV is transmitted from one person to another typically in blood and physical secretions, which includes semen.

The link between HIV/AIDS and some cancers is not entirely understood, but it probably depends on the weakening of the immune system. Most types of cancer begin when healthy cells change and develop out of control, forming a lump called a tumour. A tumor can be cancerous or benign. A cancerous tumor is malignant, which means it can develop and spread to other areas of the body. A benign tumor means the tumor can grow but will not spread.

Radiation oncology is a medical specialty that is an important component of a multidisciplinary cancer treatment approach. It works by delivering high-energy x-rays (photons) through a linear accelerator. These painless and undetectable therapeutic x-rays are used to treat a variety of malignancies.

Recent technology has combined the use of 3-D imaging technology, computerized treatment planning and high-energy x-ray machines to make more precise treatment possible. Professionals involved in radiation therapy treatment include:

Pediatric Oncology is rare, and more readily diagnosed and treated than ever. Paediatric oncology is research and cancer treatment for children and young adults. Pediatric oncologists study and train in both pediatrics and oncology. The types of cancers that develop in children are often different from cancers that develop in adults.

 Pediatric Cancer is not a single disease type, but an large group of diseases that include blood cancers (leukemia and lymphoma), brain tumors and other solid tumors of the organs, bones or soft tissues.

Molecular Oncology is a multidisciplinary basic science programme with expertise in cancer stem cells, DNA damage repair and genomic instability, tumor-host interactions, and other fundamental aspects of cancer biology.

• Discover the regulatory mechanisms that generate cellular heterogeneity and therapeutic resistance in cancer stem cells (CSCs).
• Figure out how genetic instability affects tumour heterogeneity, progression, and treatment resistance.
• Examine the relationships between cells in tumour formation, dormancy, metastasis, and therapeutic resistance, with a focus on immunological and microbiome changes.

Coronaviruses are the large group of viruses. SARS-CoV- 2 is a novel which caused a pandemic of disease named COVID-19, anyone who expose to infection and developing COVID-19. Recently, it not known that history of cancer patient increases the risk for some sickness or illness from COVID-19. Cancer and its treatment can weaken immune system and reduce your potential to against fight infections. The immune system protects our body against illness and infection caused by viruses like COVID-19.

Drug Development is the lengthy procedure because it has ability new drug must be identified and assessed in preclinical and clinical trials. Drug development medication can happen some different ways. If scientist identify new drug by examine numerous compounds in a laboratory procedure for effective ways, like killing or destroying cancerous cells. Cancer drug development is to target DNA or protein. Currently researchers are looking for whole new set of targets. Development of anti-cancer drug is evolving a step towards the invention of novel therapeutics.

Current concept of understanding the kind of cancer invent to conceptual drug design, in which new substance is developed to target a specific disease procedure. At a time, factual medication are found to be having an effectual effect against a various type of cancerous cells. New discovery lead to alteration in designs how medication reach cancerous cells present among the body, thus leading to the capacity to develop a substance. At starting procedure is referred to target and lead identification, validation, and optimization.

Vaccines are medication which helps our body to fight against disease. Vaccine can train are immune system to search and damage or destroy harmful micro-organisms, germs, and cells. There are various kind of vaccines that we receive throughout our life to prevent common sickness or illness. There are also vaccines available for tumor or cancer. There are vaccines which prevent tumor and treatment of cancer. There are vaccinations which prevent people from getting particular cancers caused by viruses. This type of vaccine will only work if a person gets the vaccination before they are infected with the virus.

Research into the molecular biology of hepatocarcinogenesis has known some biomarkers, which could offer additional evidence in order to better comprehend the biology of HCC. An abundance of biomarkers have been shown to have possible analytical implication and a wide variety of molecular markers have been verified to be excellent diagnostic tools for HCC yet it is hard to expose HCC with a single biomarker. Then, marks of a mix of biomarkers might be more imperative for the finding, arranging and visualization of HCC.   

Cancer Immunology is the branch of biology in which explore the interaction between the role of immune system or responses and progression and development of cancer. Immunotherapy or biological therapy is the treatment of cancer in which doctors boosts the natural defenses to fight cancer.  There are the three classes of immunotherapy: Immune checkpoint blockade, cellular (t-cell) transfer therapy, Monoclonal antibody and vaccination. Immunotherapy causes side effects which include pain, redness and itchiness etc.

The nervous system is common regulatory system in the human body. It is usually connected to the brain and the spinal cord through various nerves. Neuroendocrine cancers are type of cancer which rises in specialized cells. These types of cancer are rare but can occur anywhere in the body. Some cancerous cells grow rapidly and some grow slowly in the body.  Most common neuroendocrine cancer occurs in lungs, pancreas, appendix, intestines and rectum. Neuroendocrine cancer may be occurs in thymus, thyroid gland, pituitary gland and adrenal gland. Neuroendocrine cancer can be classified by site of formation.

Cancer nanotechnology is the application and uses of Nano meter product towards the identification, diagnosis, and treatment of cancer. The unique properties of nanomaterial and the connection with cells in and around the tumor micro-environment are enabling new aspects in cancer biology and therapy. The huge of applications of nanotechnology towards cancer continues to expand with exciting new developments in combination treatments, cancer immunotherapy, molecular detection, and imaging.

Scientist will provide a unique forum where scientists at every stage of their career can share unpublished, cancer discovery made possible by the use of nano particles or nano-materials. This meeting will particularly focus on two ends of the spectrum in cancer research: deepening our fundamental understanding of the interactions of nano -materials with tumors and the laboratory favourable environment, and translation of cancer nanotechnology out of the lab and into the clinic. The event will bring together a lively group of exceptional scientists in order to

(i) share cutting-edge discovery in cancer nanotechnology by expertise representing the wide range of biological sciences, engineering, and medication;

(ii) Discussion, presenting of ideas, and promote collaborations,

(iii) Enhance growth of fresh researcher during promoting variety.

Artificial Intelligence means human like intelligence performed by a computer, robot, or other machine. There is various kind of application and uses of artificial intelligence in the field of medical oncology and basic cancer research like in diagnosis, screening, imaging, drug discovering, clinical trials, pain management and treatments etc.  Recently technological uses and application of artificial intelligence in oncology are endless.

 Artificial Intelligence in Oncology covers a huge range of application in cancer management.  A new artificial intelligence (AI) system created that not only matches tumors to the best drug combinations, but does so in a way that makes sense to humans. Artificial Intelligence is expecting the best approach to cancer treatment.

Genetics is the field of biology that looks at how character passed down from parents to their children through genes. Alteration in genes called mutation, which play an important role in the building blocks of tumor. Alteration in gene can cause a cell to make proteins that affect cell growth and division into new cells. This type of alteration in genes leads to out of control cells, which can cause cancer.

Computational data mining has an ability to understand the difficulties of cancerous-related data has been caused by the application of computer and data sciences, which involve data mining, analytics, machine learning and benefits in imaging technology and probe creation. Computational modeling and simulation are orderly and cheaper tools which able to identify important temporal patterns, characteristic distinct molecular character of tumor states and other related aspects, which include tumor identification and heterogeneity, progression and metastasis, and medication resistance.

Tissue Regenerative medication is the model of renewal and restoration of damaged or destroyed tissues. As the segment for organ development and tissue restoration, stem cells have different and vast-ranging ability, thus describing their ability application and uses to tissue regenerative medication. The identification that compatible model of molecular procedure drive organ development and after birth tissue regeneration has remarkable implications for a different of cytological diseases beyond renewal biology. The examination analysis that organ-specific stem cells acquire all of the changed cells within a given tissue has led to the acceptance of a stem cell inheritance pattern for tissue development, maintenance, and repair. Extending the tissue stem cell hierarchical model to tissue tumorigenesis may transform the pattern in which we form a concept of cancer medication. A basic understanding of stem cell biology is dominant to stay knowledgeable of this mixing technology and the go along with discovery in this with field the ability in clinical application and uses.

The main agenda is to focus on new translational advances in the treatment of cancer as well as provide updates of predictable therapies for the number of the most common tumor types. The major emphasis will be clinical features of cancer treatment in this century with debate of important scientific advances underlying the novel methods still in preclinical development.

Genomics is the study of genomes. It is a field of biology which involve the structure, mapping, evolution, and editing of genomes. The genome is the whole set of DNA, which include its genes. The study of cancerous genomes has disclosed the abnormalities in DNA or genes that leads to development and growth in various ways. The invention of cancerous causing genetic and epigenetics alteration in tumor has enabled the development of therapies which target there alteration as well as treatment and diagnosis test which identifies patients who may effective from these therapies.

It’s important to range the awareness about cancer and crucial to stay away from myth and misconceptions. The internet full of myths and misconceptions related to cancer which stop patient from getting diagnosed on time and availing treatments.

This event tries to present cancer myths and misconceptions vs facts to make you aware of this disease.

Cancer patient Nurse is a professional who take cares of Cancer patients. Cancer patient nursing care could be defined as the expert care and completing the needs of patients during the time of their disease, while may involve some screening methods and preventive measures that should be taken care of patient care, fatigue, infection etc.

Cancer syndromes is the genetic disorder in which hereditary genetic alteration in single or multiple genes predispose the affected of single to the development of tumor. Cancerous syndromes display a high risk of tumor. Hereditary genetic alteration play important role in approximately 5% to 10% of all tumors. These epigenetic alterations happen at different levels, which involve decreased mass degrees of the center histones, adjusted examples of histones post-translational changes and DNA methylation, supplanting of authoritative histone along with histone changes and modification non-coding RNA articulation, in the process of organismal maturing and replicative senescence.

There are four different Stages of Cancer, which include Stage 0 – when no cancer, but some abnormal cells that may give rise to cancerous cells, Stage 1 – When Cancer is located in small area, Stage 2 & 3- When Cancerous cell has spread to larger area including tissues and lymph nodes, and Stage 4 When Cancerous cell has spread to many parts of the body.

Cancer is the major causes of death in the world. Most of the cancer can be cured if it detect at earlier stage. There are many approaches to cancer diagnose and treatment cancer that will depend on the type of cancer and stage. Cancer diagnose approaches can be more than one. You can determine diagnosis what best is for depend on your own risk. The main aim of cancer treatment is to kill or destroy cancerous cells. The treatment options are surgery, chemotherapy or Radiation etc.  Cancer treatments have many objectives, like Primary treatment, Adjuvant treatment and Palliative treatment.

“Prevention is better than cure.” – By Johann Wolfgang von Goethe.

It is extremely hard to understand why one people develop cancerous cells and another doesn’t. But some research and analysis showed that certain risk factors which may increase the chances of cancer.  Some of the common risk factors can be avoided such as lifestyle and environmental factors. Most of the researches have shown that the majority of cancers are caused by poor lifestyle like unhealthy diet, smoking and obesity. Not all cancers are preventable but we can slow down the risk of cancer by applying healthy habits, such as exercise regularly, quit smoking, limited alcohol intake etc.

Oncology is the branch of medication that deals with the prevention, diagnosis, and treatment of cancer. Survival has been enhanced due to three primary segments including enhanced counteractive action endeavours to diminish presentation to chance elements (e.g., tobacco smoking and liquor utilization), enhanced screening of some tumours (taking into consideration prior finding), and upgrades in treatment.